O Brien Florida Homes for Sale

If you've been searching for serious acreage with room to create something special, take a look at this expansive 39.69-acre cleared parcel in O’Brien, Suwannee County. With the property already cleared, you can spend less time imagining what lies beneath the brush and more time envisioning what you can do with nearly 40 acres of open Florida land. Create a private country estate with room to spread out, establish a homestead, bring your agricultural vision to life, enjoy the property for recreation, or secure a substantial tract of North Florida land for the future. The acreage provides the space and privacy that smaller parcels simply cannot offer. Located along 85th Rd in the O’Brien area, the property combines peaceful rural surroundings with access to some of North Florida's best-known natural attractions. The surrounding Suwannee Valley is known for its rivers, freshwater springs, boating, kayaking, fishing, swimming, and outdoor recreation. Whether you're dreaming of a custom home surrounded by acreage, space for animals and equipment, a family compound, recreational retreat, or simply want to own a sizable piece of Florida, this property offers an incredible canvas to make that vision a reality.

85th Road, O Brien

Listing courtesy of UNITED REAL ESTATE GALLARY. 904-500-3948

$140,000

TB8542086 MLS

Discover the possibilities with this beautiful 5-acre vacant lot located in Hawkins Estates Phase 2 in O’Brien, Florida! Enjoy the peace and privacy of country living with plenty of space to create your own vision. Whether you’re looking for a future homesite, recreational property, or an investment opportunity, this spacious parcel offers room to enjoy the relaxed North Florida lifestyle. Conveniently located with access from County Road 49 and within driving distance of O’Brien, Branford, Live Oak, and surrounding areas. Don’t miss the opportunity to own 5 acres in Suwannee County! Drive by and take a look today. Buyer and buyer’s agent to verify all information, including zoning, land use, building requirements, utilities, and property boundaries with the appropriate county authorities.

349c+R6, O Brien

Listing courtesy of CENTURY 21 ROSA LEON. 813-957-3775

$249,900

3 Beds ⋅ 1 Baths ⋅ G5116576 MLS

MOTIVATED SELLER!!! Now offering $10,000 towards closing. Escape to the country and enjoy the space and privacy of 5 beautiful acres in O’Brien! This charming 3-bedroom, 1-bath home offers 1577 square feet of living space with plenty of room to make it your own. Inside, you'll find a comfortable and functional layout, while outside is where this property really shines. With 5 acres and no HOA, there's room for a garden, animals, recreational toys, a workshop, or simply enjoying the peace and quiet of country living. Mature surroundings provide that relaxed rural feel while still keeping you within driving distance of Branford, Live Oak and Lake City. If you've been looking for a place with acreage, privacy and room to create the lifestyle you've been dreaming about, this one is worth a look. Bring your ideas and come see the possibilities this O’Brien property has to offer!

15518 192nd Street, O Brien

Listing courtesy of OPTIMA ONE REALTY, INC.. 352-243-6784

$660,000

4 Beds ⋅ 2 Baths ⋅ D6148407 MLS

MUST-SEE CUSTOM-BUILT SUWANNEE RIVER HOME WITH A NATURAL SPRING! This exceptional 2,300 SF, 4-bedroom, 2-bath custom home sits on just over 3 acres and offers approximately 400 feet of beautiful Suwannee River frontage. Designed with comfort, entertaining, and enjoying the outdoors in mind, this unique property offers an incredible North Florida lifestyle surrounded by nature and peaceful river views. Inside, the home features high ceilings, abundant natural light, and beautiful views of the Suwannee River, creating a bright and welcoming atmosphere. The spacious layout provides plenty of room for family and guests, while the home's thoughtful design and custom touches add character throughout. Outdoor living is where this property truly shines. Enjoy the floating dock and freshwater spring at the river's edge, perfect for relaxing, fishing, enjoying the water, or simply taking in the scenery. The gorgeous fenced-in yard provides a private outdoor space, while multiple outbuildings offer additional storage and versatility. A custom fire pit creates the perfect gathering spot for evenings outdoors. For entertaining, the property features a screened room with ceiling fans and a quarter bath, providing a comfortable space to enjoy the outdoors while staying protected from the elements. The spacious front porch includes a freight/automatic lift, while the back deck offers additional outdoor living space with room for a hot tub. Additional features include a tankless hot water heater, whole-house generator, covered parking, and ample storage underneath the home. The property also includes a full RV hookup with a separate septic system, making it ideal for guests, extended stays, or recreational use. With its custom-built home, expansive river frontage, natural spring, dock, acreage, multiple outdoor spaces, RV hookup, generator, and exceptional entertaining features, this is truly a one-of-a-kind riverfront property. Come experience the beauty, privacy, and possibilities this special Suwannee River retreat has to offer!

16392 198th Trace, O Brien

Listing courtesy of CENTURY 21 SUNBELT REALTY. 941-235-6610

$205,000

2 Beds ⋅ 2 Baths ⋅ GC542464 MLS

Under contract-accepting backup offers. Welcome to your private North Florida retreat! This well-maintained, furnished 2BR/2BA mobile home is situated on 6.6± wooded acres, offering the perfect blend of privacy and convenience. Tucked among mature trees, you'll enjoy a peaceful country setting while being just minutes from Fort White and Branford, with Alachua, Lake City, and Live Oak all approximately 30± minutes away. Outdoor enthusiasts will love the location being just around the corner from the world-famous Ichetucknee Springs, where you can enjoy tubing, kayaking, swimming, and hiking, along with easy access to many of North Florida's other renowned springs and rivers. The home features a two-year-old metal roof, a 2019 HVAC system, and a covered front carport for protected parking. Located just 0.3 miles from a paved road, the property offers easy access while maintaining its secluded feel. Fiber high speed internet is available, making it ideal for working remotely or streaming with ease. This property is high and dry with no HOA! Whether you're looking for a full-time residence, a weekend getaway, or an investment opportunity, this move-in-ready property offers the privacy, convenience, and outdoor lifestyle you've been searching for.

25697 21st Road, O Brien

Listing courtesy of HORIZON REALTY OF ALACHUA INC. 386-462-4020

$345,000

4 Beds ⋅ 3 Baths ⋅ GC541955 MLS

Welcome to your O’Brien oasis, a peaceful sanctuary offering the perfect blend of high-end country living and modern comfort. Situated on 4+ private, beautifully wooded acres under wide open North Florida skies, this immaculate 2021 upscale manufactured home is ready for its next steward. Step inside to an expansive, sun-drenched open-concept layout defined by large windows, crown molding, and beautiful vinyl plank flooring throughout (with cozy carpet in the bedrooms). The heart of the home features a spacious living room centered around an inviting fireplace, flowing seamlessly into the kitchen. Chefs will love the massive island, pot filler over the stove, solid wood cabinetry, ample solid surface counter space, and integrated appliances. The split bedroom floor plan offers ultimate privacy for the primary suite, which includes a generous walk-in closet, a soaking tub, and an oversized shower. A huge mud/laundry room offers additional storage and effortless everyday utility, leading out to a beautiful back deck that could be converted into a Florida room. Outside, the property is a peaceful, open canvas waiting for your personal touch. It is the perfect setup for gardening, homesteading, or simply enjoying the tranquil rural surroundings without the restrictions of an HOA. Additional features include a detached 2-car carport, a workshop, and a private well. Adventure and relaxation await just minutes from your front door. Located in a pristine area of Suwannee County, you are less than 20 minutes from three of North Florida’s absolute best freshwater springs and a convenient Suwannee River boat ramp. Whether you are looking for a full time modern homestead, a peaceful weekend retreat, or a strategic property investment, this O'Brien estate delivers unmatched space, peace, and value.

12185 198th Terrace, O Brien

Listing courtesy of KELLER WILLIAMS GAINESVILLE REALTY PARTNERS. 352-240-0600

$525,000

4 Beds ⋅ 3 Baths ⋅ GC541846 MLS

Pre-Construction. To be built. Home construction shall commence with Gibraltar Contracting LLC upon signing contract for construction with Buyer. Experience the perfect blend of quality craftsmanship and modern living in this stunning 4-bedroom, 2.5-bath Craftsman-style home. Designed with attention to detail, this home features elegant Craftsman trim, luxury vinyl plank flooring, stone countertops, and stainless steel appliances. Make it uniquely yours by choosing your preferred flooring, cabinet finishes, countertops, and fixtures to reflect your personal style. No HOA, minimal deed restrictions, and agricultural zoning provides flexibility and freedom. Don't miss this opportunity to create the home you've been dreaming of. Contact us today for more information! *Photos are from same model with some additional cost upgrades. Not actual home. Home is to be built.

TBD2 71st Lane, O Brien

Listing courtesy of ROCKFORD REALTY GROUP. 386-755-0808

07-05-S-13E-09108-040320 Riverside Drive, O Brien

$28,000

2026028307 MLS

A VACANT LOT IN O'BRIEN IN SUWANEE COUNTY!!!!

07-05-S-13E-09108-040320 Riverside Drive, O Brien

Listing Courtesy of Keller Williams Island Life RE

Selling Office: .

$69,900

G5098182 MLS

Absolutely beautiful 4 Acres awaits your dream to come true! Mobile homes are allowed, no time to build, NO HOME OWNERS ASSOCIATION, so bring your outdoor life come true. Wooded and high & dry with the opportunity to have a beautiful winding driveway to your new home.

127th Drive, O Brien

Listing courtesy of FLORIDA LAND & RANCH BROKERS. 352-242-9200

$150,000

2 Beds ⋅ 1 Baths ⋅ TB8345013 MLS

Unique Opportunity! Spacious mobile home on 5 acres of private land—perfect for those seeking space, tranquility, and nature. Ideal for living, investing, or future development. Don't miss out on this incredible property

10130 208th Path, O Brien

Listing courtesy of CENTURY 21 ROSA LEON. 813-957-3775

$21,400

R4908529 MLS

FOR SALE: 1.14 +/- acres located just a few minutes away from Royal Springs on the Suwannee River. Manufactured Homes allowed. No HOA. Only 250’ +/- off hardtop road (CR 349). River activities include boating, fishing, bird and wildlife watching, kayaking, swimming, snorkeling, tubing, wakeboarding, and waterskiing. A public boat ramp is nearby. Make your appointment today to preview this property.

143rd Drive, O Brien

Listing courtesy of TARPON REALTY, LLC. 800-495-7201

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O Brien Florida Homes for Sale

Are you looking to buy or sell a home in O Brien Florida? Call or Text (239) 880-8850 to schedule a showing on any O Brien, FL home for sale or to sell your O Brien Florida home! As Realtors specializing in the O Brien area, we can take care of all of your O Brien FL real estate needs including buying pre-existing homes, new construction homes, condominiums, land, commercial and multi-family homes in O Brien Florida. We can also help you find distressed properties in O Brien including HUD Homes, Short Sales and REO Bank Foreclosures. If you need help financing a home in O Brien, we have access to some of the best lenders that service the O Brien Florida area, including lenders that offer credit repair to buy a home and work with home builders in and near the O Brien area to help you build your home while building up your credit. If you are going to buy or sell a home in O Brien Florida, then be sure to Call or Text (239) 880-8850 Today! We are a real estate team specializing in the O Brien, FL area! Displayed are homes for sale in O Brien, FL, a city located in Florida. These O Brien Listings are updated every 15 minutes from the O Brien MLS.