Lafayette County Florida Real Estate & Homes for Sale

This property presents a unique opportunity for business-minded individuals seeking a foothold in a growing North Central Region of Florida. With a generous lot size of 1.46 acres and a 2,623 square foot building, the property offers ample space for a variety of commercial ventures. With a strategic location Halfway between Gainesville and Tallahassee Mayo, the county seat of Lafayette County, places it in a region known as the "Gateway to Growth" and is actively fostering economic development. Businesses here can benefit from a supportive environment and a focus on local prosperity in a rural and peaceful atmosphere. The property's zoning and location near the heart of Mayo make it suitable for a wide range of business possibilities. Entrepreneurs could consider a variety of service-oriented businesses, such as a specialty retail store, a professional office, a catering business, or a skilled trade service. Its proximity to other businesses in the Mayo area, as well as its presence in a region with a strong agricultural and tourism-based economy, suggests potential for a business that serves either the local community or visitors. Prospective buyers are encouraged to consult with Lafayette County's Building and Zoning departments to explore specific land-use regulations and permitting requirements, ensuring their business vision aligns with local codes. This is a rare chance to invest in a property with a strong business potential in a region poised for continued growth.

130 Ne Clyde Avenue, Mayo

Listing courtesy of RE/MAX REALTY ONE.

$89,000

3 Beds ⋅ 1 Baths ⋅ K4903894 MLS

Virtually Staged. ONE ACRE of outdoor space and a home to make your own in Mayo, Florida. Picture afternoons in the garden, meals outdoors, and room for personal projects, with local schools and downtown services nearby. This single-story, 3-bedroom, 1-bath home offers an opportunity for investors seeking a renovation project and buyers who want to personalize a home with land. Bring new life to the existing spaces, choose finishes that reflect your style, and plan how the home and outdoor areas can work together for the way you want to live. Located near downtown Mayo and the US-27 corridor, the property provides a convenient starting point for everyday errands and exploring the surrounding area. Lafayette Blue Springs State Park and the Suwannee River offer opportunities to spend time in nature, hike, fish, or paddle. For buyers who value outdoor space and the opportunity to shape a property around their plans, this one-acre setting deserves consideration.

101 Ne Schoolhouse Lane, Mayo

Listing courtesy of DC GLOBAL PARTNERS. 407-729-3006

$24,000

OM733728 MLS

Nestled at the end of a quiet cul-de-sac, this expansive 1-acre property offers the perfect blend of tranquility and opportunity. Whether you're dreaming of building your forever home or creating a private retreat, this picturesque lot provides the ideal canvas. Surrounded by lush greenery and enjoying minimal traffic, the location is perfect for families, nature enthusiasts, or anyone seeking a serene escape. Imagine waking up to the sounds of birdsong, with plenty of space for gardens, outdoor entertaining, or even a custom pool. Your dream home starts here!

Sw Roosevelt, Mayo

Listing courtesy of REAL BROKER LLC - OCALA. 855-450-0442

$369,000

OM733055 MLS

Discover 20 acres of land located along SW CR 300 near Mayo, Florida. This spacious property offers approximately 339 feet of road frontage and extends more than 2,500 feet in depth, providing plenty of room and privacy. With 20 acres to work with, the property offers potential for a homesite, recreational use, agricultural activities, livestock, or a private country retreat, subject to county zoning and permitting requirements. Enjoy the peaceful rural setting of Lafayette County while remaining convenient to Mayo and surrounding North Florida communities.

TBD Sw Cr 300, Mayo

Listing courtesy of CENTRAL CITY REALTY. 352-456-1941

$600,000

3 Beds ⋅ 3 Baths ⋅ O6440305 MLS

Welcome to 190 SE Riverside West Branford, where the beauty of waterfront living meets an incredible investment opportunity. Whether you’re looking for a peaceful riverfront retreat, a full-time residence, or a furnished property with income-producing potential, this unique property offers the flexibility to make it your own. Step inside to a fully furnished home designed for easy living and immediate enjoyment. Imagine starting your mornings with the water just outside your door, spending afternoons relaxing by the river, and ending the day taking in the peaceful surroundings. Here, the lifestyle is just as valuable as the property itself. For the investor, the property presents an exciting opportunity to capitalize on the demand for waterfront accommodations. For the owner-occupant, it’s an opportunity to leave the ordinary behind and embrace a slower pace surrounded by nature and water. Move in. Rent it. Escape to it. The choice is yours. If you’ve been searching for a waterfront property that offers both lifestyle and investment potential, this is one you won’t want to miss. Come experience riverfront living and discover everything 190 SE Riverside West Branford has.

190 Se Riverside West Drive, Branford

Listing courtesy of 15 PROPERTIES. 561-716-8388

$47,000

A4705261 MLS

SUNNY OAKS SUBDIVISION land of 2.12 AC! Build your dream home and enjoy your nature and privacy. Another parcel by it is available for purchase as well (listing #A4705258).

Sw Oakdale Road, Mayo

Listing courtesy of 7REALTY LLC. 229-415-5545

$43,000

A4705258 MLS

SUNNY OAKS SUBDIVISION land of 1.74 AC! Build your dream home and enjoy your nature and privacy. Another parcel by it is available for purchase as well (listing #A4705261).

Sw Oakdale Road, Mayo

Listing courtesy of 7REALTY LLC. 229-415-5545

$27,500

OM730965 MLS

IMPROVED PRICE! Discover Your North Florida Get-Away! This wooded lot in Mayo, FL offers the opportunity to create your own private retreat in a peaceful natural setting surrounded by the outdoor recreation North Florida is known for. Located in Canoe Country, residents have access to the private boat ramp on the Suwannee River, making it easy to enjoy boating, kayaking, fishing and exploring the nearby waterways. Only about 12 miles to Troy Springs, a popular destination for swimming, paddling, and enjoying the crystal-clear spring waters. Additionally, Steinhatchee is roughly 25 miles where you can enjoy the Gulf waters. Live Oak and Perry are also within driving distance for shopping and dining. Whether you're looking for a permanent home, create a weekend retreat, or secure a piece of North Florida property close to some of the area's best natural attractions, this wooded lot offers plenty of possibilities. Buyers should always perform their own due diligence to verify property dimensions and any other information.

Nw West South Drive, Mayo

Listing courtesy of EXP REALTY LLC. 888-883-8509

$59,000

GC541349 MLS

Build your dream home on this beautiful 5-acre parcel just outside of Branford. You'll appreciate the mature Oak Trees that provide shade and also being on a paved county road. This property offers the perfect setting for country living. Plenty of room for a home, barn, workshop, and animals with easy access to the Suwannee and Santa Fe Rivers. A peaceful North Florida setting with endless possibilities!

7563 Se County Road 405, Branford

Listing courtesy of BHGRE THOMAS GROUP. 352-226-8228

$2,800,000

6 Beds ⋅ 3 Baths ⋅ GC539503 MLS

A truly extraordinary and incredibly rare opportunity awaits with this one-of-a-kind 66-acre multi-family estate, privately nestled in a peaceful and picturesque country setting. Whether you’re searching for a high-income-producing investment, a private family compound, an unforgettable hunting and fishing retreat, or a legacy property to enjoy for generations, this remarkable estate offers unmatched versatility, privacy, and endless potential. Surrounded by natural beauty and thoughtfully designed for both comfort and functionality, the property features five residential buildings strategically positioned throughout the acreage to create a sense of privacy and independence. Approximately 57 acres showcase a beautiful mix of open land and wooded surroundings, while an additional privately owned 9-acre portion of Lake Adam provides stunning water views, peaceful lake access, and a breathtaking backdrop rarely found in today’s market. The property is also conveniently located near the famous Suwannee River, making it ideal for outdoor enthusiasts who enjoy boating, fishing, hunting, and year-round recreation. A large open area along the entrance road creates incredible flexibility for future expansion and development opportunities, whether your vision includes additional residences, RV sites, gardens, livestock, recreational amenities, event space, or an expanded retreat-style setting. With over 9,100 square feet of permitted building area, the property is uniquely suited for a wide variety of uses including long-term rentals, short-term vacation rentals, employee housing, multi-generational living, or a private estate compound. Built between 1997 and 2019, the residences feature durable commercial-style modular metal construction with full insulation and quality interior finishes, offering the perfect blend of low-maintenance durability and comfortable living. Each residence is individually equipped with its own private well, septic system, and electric meter, creating convenience, efficiency, and true independence for both owners and tenants. Unlike traditional rental communities, each home enjoys approximately one to two acres of private yard space, providing residents with a spacious and peaceful environment to relax and enjoy the beauty of country living. Community-style amenities further enhance the property’s appeal, including a screened-in swimming pool and private lake access that invite endless relaxation and outdoor enjoyment. Properties offering this level of acreage, infrastructure, privacy, water frontage, and income-producing potential are exceptionally difficult to find. Whether your dream is to create a thriving rental portfolio, establish a private family retreat, develop a destination getaway, or secure a long-term investment with limitless possibilities, this truly remarkable property is ready to make that vision a reality.

401 Se Falcon Road, Branford

Listing courtesy of WATSON REALTY CORP- TIOGA. 352-274-2600

$19,950

OM718650 MLS

Under contract-accepting backup offers. Discover the perfect opportunity to create your own slice of country living on this beautiful 1-acre residential lot in Lafayette County. Zoned residential, this spacious parcel offers the freedom and flexibility buyers are looking for—whether you're dreaming of building a custom home, starting a mini farm, or simply enjoying more privacy and open space. With plenty of room for a garden, chickens, small livestock, workshop, RV parking, or outdoor entertaining, this property is ideal for those seeking a quieter lifestyle without sacrificing convenience. Enjoy wide-open skies, fresh air, and the peace that comes with having space between you and your neighbors. Bring your builder, your animals, and your vision—this property is ready for your dream home and homestead plans. Opportunities like this don’t last long. Secure your acre of possibility today!

00 Sw Doe Road, Mayo

Listing courtesy of REAL BROKER LLC - OCALA. 855-450-0442

$20,000

TB8462749 MLS

Location! Location! Location! Beautiful parcel of land in Mayo, FL waiting for you to build your dream home. Please verify all information. Measurements are estimates. All offers are welcomed.

San Pedro Avenue, Mayo

Listing courtesy of KELLER WILLIAMS SUBURBAN TAMPA. murraycoleman@kw.com

$15,000

TB8458797 MLS

Tucked away in the heart of Old Florida, this 1.44-acre wooded lot offers a rare blend of privacy, nature, and river access. Surrounded by mature trees and alive with twinkling fireflies at night, this peaceful property is perfect for those looking to slow down and enjoy the outdoors. Enjoy community access to the historic Suwannee River, complete with a boat ramp just steps away—ideal for boating, fishing, kayaking, and soaking in the natural beauty of the area. Bring your RV, camper, or ATV and make it your weekend getaway or future homesite. The lot is buildable, with homes and septic systems required to be elevated to meet current floodplain standards, allowing you to design with peace of mind. Located in a quiet, friendly small-town setting, this property offers tranquility without sacrificing a sense of community. An affordable HOA of just $60/year keeps things simple and covers road maintenance, preserving the natural feel of the neighborhood while ensuring easy access. Whether you’re dreaming of a rustic retreat, an outdoor basecamp, or a future elevated home near the river, this property delivers space, serenity, and classic Florida charm.

Nw Fox Run Trail Unit 107, Mayo

Listing courtesy of EXP REALTY LLC. 888-883-8509

$10,000

223083379 MLS

Dont miss your opportunity to own this vacant wooded lot perfect for your mobile, modular, or custom-built home. This is 2 lots being sold together to total approximately 2.18 acres in size, close to the Suwannee River in Branford, FL. Lot is wooded for privacy and has Eastern rear exposure and is approximately 300' x 317 x 300'x 317'! NO Deed Restrictions or HOA Fees in this community so bring your RV & Boat. Quick access to County Rd 490, Hatchbend Conservation Area, and only a short drive to shopping and dining areas and more. Well, Septic, & Electricity needed if improving the land. Bring the boat, fishing poles, & jet skis to enjoy the many water activities all close by. Quiet country area & inventory is LOW surrounding this property, call today to make this land yours!

Branford

Courtesy of Allison James Estates & Homes

Selling Office: .

$22,000

222090793 MLS

Dont miss your opportunity to own this vacant wooded lot perfect for your mobile, modular, or custom-built home. Land is approximately 2.18 acres in size, close to the Suwannee River in Branford, FL. Lot has Eastern rear exposure and is approximately 301' x 318'! NO Deed Restrictions or HOA Fees in this community so bring your RV & Boat. Quick access to County Rd 490, Hatchbend Conservation Area, and only a short drive to shopping and dining areas and more. Well, Septic, & Electricity needed if improving the land. Bring the boat, fishing poles, & jet skis to enjoy the many water activities all close by. Quiet country area & inventory is LOW surrounding this property, call today to make this land yours!

SE Wild Turkey Road SE, Branford

Courtesy of Allison James Estates & Homes

Selling Office: .

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Lafayette County Florida Real Estate & Homes for Sale

Are you looking to buy or sell a home in Lafayette County Florida? Call or Text (239) 880-8872 to schedule a showing on any Lafayette County, FL home for sale or to sell your Lafayette County Florida home! As Realtors specializing in the Lafayette County area, we can take care of all of your Lafayette County FL real estate needs including buying pre-existing homes, new construction homes, condominiums, land, commercial and multi-family homes in Lafayette County Florida. We can also help you find distressed properties in Lafayette County including HUD Homes, Short Sales and REO Bank Foreclosures. If you need help financing a home in Lafayette County, we have access to some of the best lenders that service the Lafayette County Florida area, including lenders that offer credit repair to buy a home and work with home builders in and near the Lafayette County area to help you build your home while building up your credit. If you are going to buy or sell a home in Lafayette County Florida, then be sure to Call or Text (239) 880-8872 Today! We are a real estate team specializing in the Lafayette County, FL area! Displayed are homes for sale in Lafayette County, FL, a county located in Florida. These Lafayette County Listings are updated every 15 minutes from the Lafayette County MLS.

Lafayette County Florida Real Estate & Homes for Sale

Lafayette County Florida Real Estate & Homes for Sale

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