New Port Richey Florida Commercial Properties for Sale

New Port Richey Florida Commercial Properties for Sale

$395,000
TB8540125 MLS
Directly across from Morton Plant North Bay Hospital, BayCare’s 222-bed acute-care facility and West Pasco County’s only not-for-profit community hospital. This single-story commercial building occupies a rare, irreplaceable location in an active medical corridor. The hospital campus generates continuous daily traffic of patients, staff, physicians, and visitors, creating durable demand for nearby professional and medical-related space that cannot be replicated. The property was fully renovated in 2026 and is currently vacant, delivered as a vanilla shell ready for immediate owner-occupant build-out or NNN lease-up. No existing tenants. Available for immediate occupancy. Constructed of concrete block with stucco exterior and central HVAC, it sits on a 6,534 SF lot with on-site paved parking. It lies within the New Port Richey Community Redevelopment Area (CRA 2002), benefiting from ongoing public investment in infrastructure and corridor improvements. Pasco County’s office submarket currently operates at approximately 4.9% vacancy with average asking rents near $27/SF, reflecting landlord-favorable conditions. Stabilized NNN rents in the $22–$26/SF range are supported by medical-adjacent comps and broader submarket data, positioning the asset for strong cash-flow potential or a high-yield investment exit. At the offered price of $395,000 (~$220/SF), the property is priced attractively relative to replacement cost and the hospital-adjacent premium, appealing to both medical/professional owner-occupants and private investors. Ideal for healthcare practitioners (primary care, physical therapy, behavioral health, specialty clinics), medical billing or ancillary services, professional offices (legal, accounting, insurance, financial services), or as a 1031 exchange or NNN investment vehicle. The combination of hospital adjacency, recent full renovation, on-site parking, CRA location, and constrained supply of comparable medical-corridor sites creates a compelling ownership opportunity in a growing West Pasco market.

6102 Indiana Avenue, New Port Richey

Listing courtesy of RE/MAX PREMIER GROUP. 813-929-7600

$1,300,000
TB8538515 MLS
TURNKEY MEDICAL/PROFESSIONAL OFFICE ON STATE ROAD 54! Excellent opportunity to own a beautifully remodeled commercial property located at 4911 State Rd 54 in New Port Richey. Previously utilized as a medical office, this well-maintained property offers a functional, move-in-ready layout ideal for a variety of medical, healthcare, wellness, or professional office uses. The updated interior features a bright, modern design with luxury-style flooring, recessed lighting, fresh neutral finishes, multiple private offices/exam rooms, administrative and workspace areas, ample cabinetry and counter space, and multiple sinks throughout—providing excellent flexibility for a new owner or occupant. The property also features a 2017 roof, security alarm system with surveillance cameras, and generous on-site parking. The attractive brick exterior and professional appearance provide excellent curb appeal, while its location directly along the State Road 54 corridor offers convenient access for clients, patients, and staff. Whether you’re looking to establish or expand a medical practice, therapy or wellness center, dental or specialty office, professional services firm, or other commercial operation, this property offers the advantage of an already renovated space with a highly functional layout. Move-in ready, remodeled, and positioned along one of New Port Richey’s primary commercial corridors—an excellent opportunity for an owner-user or investor.

4911 State Road 54, New Port Richey

Listing courtesy of REAL BROKER, LLC. 855-450-0442

$235,000
TB8529533 MLS
Set right along FL-54 in New Port Richey, 4923 FL-54 puts you in the middle of one of Pasco County's most convenient corridors. This Mixed property is all about location and possibility, offering the perfect blank canvas for buyers, investors, or dreamers ready to roll up their sleeves. The setting couldn't be easier. Local grocery sits just over a mile away, keeping everyday errands quick and simple. School is close by for families, and nearby parks with green spaces add a welcome touch of calm to the neighborhood. With major roads only steps from your door, commuting, shopping, and weekend outings are effortless. Downtown New Port Richey, Gulf beaches, and dining spots are all within comfortable reach, giving you the best of relaxed Florida living. What truly sets this property apart is its renovation potential. This 2-bedroom, 1-bathroom, nice sized fenced backyard home is ready for a fresh vision, the opportunity here is wide open. The high-visibility FL-54 frontage also opens the door to creative possibilities, making this a rare find in a growing area. Roof is less than 6 months old! Properties like this—priced with room to build sweat equity in such a connected location—don't come along often. Bring your ideas, your tools, and your imagination, and turn this diamond in the rough into something special. Schedule your private showing today before this opportunity slips away!

4923 State Road 54, New Port Richey

Listing courtesy of KELLER WILLIAMS RLTY NEW TAMPA. 813-994-4422

$259,000
TB8523098 MLS
NOW IS THE TIME to establish, relocate, or expand your business in one of New Port Richey's most desirable commercial locations! This exceptional TURN-KEY OFFICE presents a rare opportunity to position your company in the HEART OF DOWNTOWN on highly sought-after MAIN STREET, where your business will benefit from HIGH VISIBILITY, excellent road frontage, and an estimated 6,000-12,000 vehicles passing daily. Whether you're an entrepreneur launching your next venture, an established company seeking greater exposure, or an investor looking for a quality commercial asset, this property delivers the location, presence, and flexibility to help your business thrive. Perfectly suited for a Professional Office, Medical or Wellness Practice, Attorney, CPA or Accounting Firm, Financial or Insurance Services, Real Estate or Mortgage Company, Title Agency, Consulting Firm, Marketing or Technology Company, Engineering or Architectural Firm, Counseling or Therapy Practice, Chiropractic Office, Education or Tutoring Center, Executive Suites, Startup Headquarters, Boutique Retail, Showroom, or a wide variety of other professional business uses. Step inside to discover a bright, modern, and professional interior featuring a RECEPTION AREA, THREE PRIVATE OFFICES, a LARGE CONFERENCE / MEETING ROOM, KITCHEN/BREAK ROOM, UPDATED FLOORING, CENTRAL A/C, and a FLEXIBLE FLOOR PLAN designed to adapt to your business needs. Every functional component has been well maintained, allowing the next owner or tenant to move in and begin operating immediately. The exterior is equally impressive with a METAL ROOF, SECURITY CAMERAS, FULLY FENCED PROPERTY, and a PRIVATE ASPHALT PARKING LOT offering FIVE PARKING SPACES with room to add more—an exceptional advantage in the downtown corridor. Positioned on a PRIME CORNER LOT within an established business district surrounded by restaurants, retail, and professional services, this property offers EXCELLENT SIGNAGE OPPORTUNITIES, easy accessibility, and a direct drive to the Gulf. Located in FLOOD ZONE X with NO HOA FEES, it also provides added long-term value and lower ownership costs. Commercial opportunities combining a PRIME MAIN STREET LOCATION, HIGH TRAFFIC, MOVE-IN READY CONDITION, PRIVATE PARKING, and exceptional exposure rarely become available. If you've been waiting for the right place to grow your business, strengthen your brand, and establish a lasting presence in one of New Port Richey's most active commercial corridors, this is the opportunity you've been waiting for. Schedule your private showing today!

6511 Main Street, New Port Richey

Listing courtesy of COMPASS FLORIDA LLC. 727-380-2067

$1,250,000
TB8518428 MLS
Under contract-accepting backup offers. We are proud to represent 5701 Main Street, New Port Richey, FL 34652 (“the Property”) for sale. The Property offers a rare opportunity to acquire a 3,000 SF commercial building located on Main Street in the heart of Downtown New Port Richey. With prominent street frontage, flexible Downtown zoning, rear access, designated parking, and adjacency to public parking, the Property is well-positioned for an owner-user or investor seeking a highly visible location within one of Pasco County’s most active historic downtown corridors. The Property is currently occupied and configured as a financial planning office and will be delivered vacant at closing. The existing layout includes private offices, a conference room, reception/check-in area, open workstation space, a remodeled kitchen/break area, three restrooms, and both front and rear building access. Originally built in 1956, the single-story building is improved with concrete block/stucco construction and a built-up tar and gravel roof covering. 5701 Main Street is located within the City of New Port Richey’s Downtown zoning district, a flexible mixed-use district intended to support a variety of downtown uses, including office, retail, restaurant, service, and other compatible uses. This provides future ownership with flexibility for continued office use or potential repositioning, subject to buyer verification and applicable city approvals. The Property is surrounded by the growing energy of Downtown New Port Richey, with nearby restaurants, bars, breweries, cafés, boutique retailers, Sims Park, the Cotee River, and the historic Hacienda Hotel. Nearby dining and entertainment options include The Social NPR, Cotee River Brewing Company, Ordinance One, Bourbon on Main, Herschel’s Scratch Kitchen, BackDraughts Wood Fired Pizza, Estuary, SteamWorks Pub, Sasha’s on the Park, Emerald Coast Brewing Company, and other downtown operators. Downtown New Port Richey continues to benefit from public and private investment, including the Main Street Landing mixed-use project, which includes 80 multifamily units and 13,640 SF of retail space, the Residences at Orange Lake, the historic Hacienda Hotel renovation, and continued improvements around James E. Grey Preserve and other city projects. 5701 Main Street offers a compelling opportunity to acquire a well-located commercial building in a walkable downtown setting with immediate owner-user functionality, flexible zoning, and long-term repositioning potential.

5701 Main Street, New Port Richey

Listing courtesy of KELLER WILLIAMS TAMPA PROPERTIES. 813-264-7754

$849,000
W7886425 MLS
INCLUDES 4 ADDRESSES ON ONE PARCEL 6112 GRAND BLVD., 6114 GRAND BLVD., 6118 GRAND BLVD. AND 6124 GRAND BLVD., NEW PORT RICHEY FLORIDA AND BUSINESS, MASTER MECHANICS OF NEW PORT RICHEY, INC. ***Highly sought after Commercial Property within the City of New Port Richey on heavily traveled connecting thoroughfare from Main Street, Grand Blvd running North and South and includes a Grandfathered Automotive Service Business with a history spanning 53 years and the only automotive repair business within the downtown City of New Port Richey. High visibility with every parade parade held in the City of New Port Richey traversing past this site. The March 21, 2026 street parade featured more than 100 entries winding through Grand Blvd., Main Street, Sims Park and Orange Lake and drew tens of thousands of spectators. Sale will include the Corporation MASTER MECHANICS OF NEW PORT RICHEY, INC. with grandfathered business, inventory (inventory list available), intellectual property, phone numbers, web site, signage, Mitchell Software which contains 3600+/- client list and contact data of ongoing customers and their family members for three generations (former software, Info Max still available as well) plus more. Sale also includes all real estate consisting of a corner lot with 350 feet of road frontage, 150 feet directly on Grand Blvd. and 3 rental units one hundred percent occupied in addition to the Automotive Repair Business. Rents are below market and contribute $1,150.00 per month to the overall income. Currently additional retail buildings are occupied by a wonderful florist, talented hairdressers and a fabulous consignment shop with many wears. Tenants are month to month. Very clean financials with more than a 4 year financial history. Business has steadily increased year to year due to rising costs of new automobiles. Most family's are opting to repair as apposed to buy new. NOI of almost 200K per year and at the current asking price provides a spectacular 22% CAP rate. Don't miss out on this rare opportunity. Real Estate only without the automotive business, inventory etc. is also available please see MLS W7886156

6118 Grand Boulevard, New Port Richey

Listing courtesy of RE/MAX MARKETING SPECIALISTS. 727-853-7801

$849,000
W7886158 MLS
INCLUDES 4 ADDRESSES ON ONE PARCEL 6112 GRAND BLVD., 6114 GRAND BLVD., 6118 GRAND BLVD. AND 6124 GRAND BLVD., NEW PORT RICHEY FLORIDA AND BUSINESS, MASTER MECHANICS OF NEW PORT RICHEY, INC. ***Highly sought after Commercial Property within the City of New Port Richey on heavily traveled connecting thoroughfare from Main Street, Grand Blvd running North and South and includes a Grandfathered Automotive Service Business with a history spanning 53 years and the only automotive repair business within the downtown City of New Port Richey. High visibility with every parade parade held in the City of New Port Richey traversing past this site. The March 21, 2026 street parade featured more than 100 entries winding through Grand Blvd., Main Street, Sims Park and Orange Lake and drew tens of thousands of spectators. Sale will include the Corporation MASTER MECHANICS OF NEW PORT RICHEY, INC. with grandfathered business, inventory (inventory list available), intellectual property, phone numbers, web site, signage, Mitchell Software which contains 3600+/- client list and contact data of ongoing customers and their family members for three generations (former software, Info Max still available as well) plus more. Sale also includes all real estate consisting of a corner lot with 350 feet of road frontage, 150 feet directly on Grand Blvd. and 3 rental units one hundred percent occupied in addition to the Automotive Repair Business. Rents are below market and contribute $1,150.00 per month to the overall income. Currently additional retail buildings are occupied by a wonderful florist, talented hairdressers and a fabulous consignment shop with many wears. Tenants are month to month. Very clean financials with more than a 4 year financial history. Business has steadily increased year to year due to rising costs of new automobiles. Most family's are opting to repair as apposed to buy new. NOI of almost 200K per year and at the current asking price provides a spectacular 22% CAP rate. Don't miss out on this rare opportunity. Real Estate only without the automotive business, inventory etc. is also available please see MLS W7886156

6118 Grand Boulevard, New Port Richey

Listing courtesy of RE/MAX MARKETING SPECIALISTS. 727-853-7801

$595,000
TB8497632 MLS
Location, Location, Location! Historic Downtown New Port Richey is booming, and this Main Street location places you right in the center of the momentum. This 1,900 SF Professional Office Building offers outstanding visibility, steady traffic, and the rare advantage of a new public parking lot immediately adjacent to the property, plus additional street parking along Main Street. As new restaurants, shops, parks, and businesses continue to energize the downtown district, this location is perfectly positioned for long term success. The single story layout includes three restrooms and a multi room configuration that most recently operated as a long standing dental office. The existing layout provides an excellent foundation for a wide variety of uses including medical, dental, wellness, legal, financial services, salon suites, executive offices, or general professional office space. The interior is ready for renovation, offering a fantastic opportunity to design and build out a customized space tailored to your business or investment vision. The current configuration also lends itself to the potential for multiple suites, making this an attractive option for multi-tenant income, professional office condos, or an owner occupant looking to offset expenses. Concrete block construction, strong Main Street presence, and walkable downtown surroundings add to the appeal. Recent updates include a new roof in 2023 and 2 brand new rooftop HVAC systems in 2023. With downtown New Port Richey quickly becoming one of the most exciting and active areas in the region, this property offers a chance to establish and expand your presence in a location surrounded by a thriving and in-demand community.

5838 Main Street, New Port Richey

Listing courtesy of LPT REALTY, LLC. 877-366-2213

$1,300,000
W7879367 MLS
Welcome to a rare opportunity in the heart of Ridge Road frontage—6.19 acres of versatile land with a custom pool home, private fishing pond, and zoning that allows residential, agricultural, and C2 commercial uses. Whether you’re dreaming of a private retreat, a working farm, or a business hub, this property has the space and flexibility to make it happen. The Home 4 bedrooms, 4 full baths, 2 half baths Wraparound porch with swing for relaxing country evenings Great room with real wood-burning stove for cozy winters Formal dining room large enough for a farmhouse table and hutch Monstrous gourmet kitchen with solid oak cabinets, granite countertops, and a patented center island with swivel stools Master suite and 4th bedroom/office/den on the main floor Two upstairs bedrooms with private baths; one includes an adjoining room ideal for a nursery, home office, or sitting area Over 1,065 sq. ft. of covered, tiled lanai for entertaining Huge 50’ x 30’ pool with slide for year-round fun The Land & Extras 6 acres of Ridge Road frontage plus dual access (Ridge Road & Creston) Private fishing pond and space for your own driving range Barn for equipment, RV, or boat storage Asphalt parking lot already in place with two entrances Existing sheds for storage or workspace Public water to the home; wells and septic for commercial/agricultural use Wildlife all around—deer, birds, and open skies Business Potential With C2 zoning, you have up to 42 potential business uses—including storage units, plant nursery, roofing contractor headquarters, or event planning. The home itself is also a perfect setup for an Airbnb, wedding venue, or retreat center. This is not just a property—it’s a lifestyle and a business opportunity wrapped into one. Space, seclusion, and unmatched flexibility make this estate truly one of a kind. Schedule a private showing today and explore how this property can fit your dreams. Also being sold as residential MLS# 7879848

9215 Ridge Road, New Port Richey

Listing courtesy of RE/MAX CHAMPIONS. 727-807-7887

$589,988
TB8348638 MLS
Seize this rare opportunity to own a 2,300+ sq. ft. commercial property situated on over an acre along Little Road, a highly traveled six-lane corridor offering outstanding exposure and accessibility. With close proximity to SR 52, US-19, the Suncoast Parkway, and public transportation, this location is ideal for businesses seeking visibility and convenience. Formerly operated as a chiropractic office, the property is designed for maximum flexibility, making it suitable for a wide range of professional, medical, or commercial uses. The building features no interior load-bearing walls, allowing for easy customization and reconfiguration to fit your business needs. Two curb cuts and a circular driveway provide seamless ingress and egress, while over a dozen paved parking spaces accommodate clients and staff. The property also offers an ADA-compliant entrance ramp and restroom, a spacious reception area with administrative office space, an integrated garage/storage area, a kitchen or break room for staff convenience, and a functional illuminated monument sign for excellent street visibility. The load-bearing structural setup supports easy interior modifications. Additional amenities include two full bathrooms and two half bathrooms, a rear screened porch, and a paved rear patio, offering flexibility for expansion, outdoor workspace, or guest-use areas. A new roof installed in 2020 adds long-term value and peace of mind. In addition to its commercial appeal, the property also presents a unique opportunity for conversion to an income-producing short-term rental or Airbnb-style use, subject to zoning and local regulations, making it attractive to investors seeking versatility and multiple revenue streams. This highly visible, easily accessible, and adaptable property offers endless possibilities. Schedule your private tour today and explore the potential!

10129 Little Road, New Port Richey

Listing courtesy of KELLER WILLIAMS REALTY- PALM H. 727-772-0772

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New Port Richey Florida Commercial Properties

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