Refine Search
Sort by
$699,000
4 Beds 2 Baths GC542408 MLS
Welcome to your own private slice of North Florida paradise! Nestled on **5 picturesque acres** in the peaceful community of **Melrose**, this beautifully maintained **4-bedroom, 2-bathroom** home offers the perfect blend of country charm, modern comfort, and exceptional outdoor living. From the moment you arrive, you'll be captivated by the inviting **covered front porch**, complete with a classic porch swing—the perfect spot to enjoy your morning coffee, unwind after a long day, or simply take in the peaceful surroundings. Inside, you'll find a spacious, thoughtfully designed floor plan with plenty of room for family and guests. The home features four comfortable bedrooms, two well-appointed bathrooms, and an **oversized attached garage**, providing ample space for vehicles, tools, hobbies, and additional storage. Step outside and discover an outdoor oasis designed for year-round enjoyment. Cool off in the sparkling **in-ground fiberglass swimming pool**, protected by a screened enclosure that allows you to enjoy Florida's beautiful weather with added comfort and convenience. Whether you're entertaining friends, hosting family gatherings, or relaxing poolside, this backyard retreat is sure to impress. Beyond the pool lies one of the property's most unique features—an **active pecan orchard** and pear trees that creates a beautiful backdrop while offering seasonal harvests and a true taste of country living. The expansive acreage provides privacy, room to roam, and endless opportunities for gardening, recreation, or simply enjoying the natural beauty of the property. Need space for your toys, equipment, or hobbies? You'll love the impressive **metal outbuilding**, designed with functionality in mind. Featuring **two roll-up doors**, the drive-through design easily accommodates a boat, RV, trailers, or recreational vehicles. A large, enclosed storage room provides secure space for tools and equipment, while generous workshop areas on both sides of the building offer endless possibilities for woodworking, mechanics, crafts, or running a home-based business. Located in the charming Melrose area, this exceptional property offers the tranquility of rural living while remaining within easy driving distance of Gainesville, Palatka, and the area's many lakes, parks, and outdoor recreation opportunities. If you've been searching for a property that offers privacy, acreage, a pool, abundant storage, and room to live the lifestyle you've always dreamed of, this remarkable home truly has it all.

8140 Meadowlark Ct, Melrose

Listing courtesy of PLATINUM REAL ESTATE. 888-974-7253

$599,000
3 Beds 2 Baths GC542295 MLS
Looking for a private hideaway where you can slow down and enjoy the peaceful country lifestyle? Welcome to this one-of-a-kind retreat nestled on nearly 19 beautiful acres in Melrose. This custom home is filled with warmth and character, featuring stunning hardwood floors, exceptional custom woodwork throughout, and a spacious great room highlighted by a soaring vaulting ceiling and cozy wood-burning fireplace. Expansive covered front and back porches stretch the full length of the home, providing the perfect place to relax, entertain, or simply take in the peaceful views of the surrounding property. Outside, the possibilities are endless. With nearly 19 acres, there's plenty of room for horses, gardening, outdoor recreation, or creating your own private homestead. Whether you're seeking a full-time residence or a weekend country escape, this property offers the perfect blend of privacy, comfort, and natural beauty. Come experience everything this country retreat has to offer!

22304 Ne 35th Avenue, Melrose

Listing courtesy of CB ISAAC REALTY. 352-475-2199

$495,000
3 Beds 2 Baths GC542254 MLS
Welcome to Lilly Lake, where peaceful lakefront living meets stylish modern comfort. Nestled on the crystal-clear, spring-fed waters, this fully upgraded 3-bedroom, 2-bath home offers the perfect retreat from the hustle and bustle of city life. Step inside to a bright, sun-filled interior featuring luxury vinyl flooring throughout, a cozy wood burning fireplace, and tasteful designer finishes that create a warm yet elegant atmosphere. Every detail has been thoughtfully updated, making this home truly move-in ready. The outdoor living space is just as impressive. A spacious lakefront deck provides the perfect setting for entertaining guests, enjoying morning coffee, or simply taking in the breathtaking views. Down by the water, you'll find your own private boat ramp, boat lift, and an elevated sitting area-ideal for watching sunsets or relaxing by the lake. If you've been dreaming of peaceful waterfront living with modern upgrades and year-round recreation, this is the perfect home.

8443 Lilly Lake Road, Melrose

Listing courtesy of CB ISAAC REALTY. 352-475-2199

$795,000
6 Beds 4 Baths GC541579 MLS
Where Lake Life Meets Country Comfort 8315 Lilly Lake Road • Melrose, Florida • $795,000 Imagine waking up beneath a canopy of mature oaks, spending your afternoons beside the pool, and ending the day with the peaceful beauty of private Lake Opal just beyond your door. Welcome to a truly special Melrose retreat—an expansive 4,425-square-foot brick home nestled on 1.69 acres of picturesque lakefront property. Designed for both comfortable everyday living and unforgettable gatherings, this six-bedroom, four-bath home offers the space, flexibility, and setting today's buyers are looking for. Inside, the heart of the home is the generous kitchen and inviting family spaces, where gatherings naturally become the centerpiece of everyday life. A spacious family room flows into a dedicated game room, complete with a pool table and built-in ping-pong table—creating an ideal setting for holidays, weekend guests, or simply enjoying time together. Need room for everyone? You have it. The home includes six bedrooms, the in-law suite features its own private entrance—perfect for extended family, guests, multigenerational living, or a private home office arrangement. One bedroom offers excellent flexibility as a dedicated office, study, or creative space. Storage is anything but an afterthought. A huge pantry/storage area, large laundry room with built-in drop zone and ironing board, plus additional storage beneath the pool deck provide practical solutions for everything from everyday organization to outdoor equipment. And then there is the lifestyle. Step outside and enjoy your own private oasis with a pool, hot tub, lake views, fenced yard, dog run, RV hookup, and oversized parking. Mature trees provide shade and privacy while Lake Opal creates a beautiful backdrop for quiet mornings, weekend recreation, fishing, swimming, and sunset gatherings. With a metal roof, brick exterior, private well and septic system, this property combines enduring construction with the relaxed appeal of lake-country living. Located in the Melrose/Keystone Heights area, the property offers a peaceful retreat while remaining conveniently positioned for access to Gainesville, Ocala, St. Augustine, and Jacksonville. More Than a Home—It's a Place to Gather, Unwind & Make Memories. Whether you're looking for a spacious primary residence, a multigenerational home, a private lake retreat, or simply a property where family and friends can come together, 8315 Lilly Lake Road offers an uncommon combination of space, privacy, recreation, and waterfront living. Come experience Lake Opal living for yourself.

8315 Lilly Lake Road, Melrose

Listing courtesy of CLASSIC PROPERTIES OF NORTH FLORIDA. 352-331-2100

$370,000
3 Beds 2 Baths GC542185 MLS
Welcome to a beautiful waterfront retreat in the heart of Lake Geneva Estates in Melrose, Florida—where everyday living feels like a private getaway. This exceptional 3-bedroom, 2-bath canal-front home offers the perfect rural living: sweeping water views underneath the most beautiful oak trees. From the moment you arrive, the paved driveway leads you to an inviting entrance that sets the tone for what’s inside. Step through the door into a spacious open-concept living area where high ceilings and a panoramic layout seamlessly connect the living room, kitchen, and dining space. The kitchen is designed for both function and gathering, featuring abundant counter space and sleek stainless steel appliances. Anchoring the living room is a warm brick wood-burning fireplace, creating a cozy focal point that flows naturally into the Florida room—where walls of windows showcase stunning canal and island views. The primary suite is a peaceful retreat with a generous walk-in closet and a private en-suite bath. An interior utility room adds everyday convenience and functionality. Outdoor living is where this property truly shines. An oversized garage provides ample storage, while the screened lanai invites you to relax and take in serene views of the canal just beyond your backyard. A patio overlooks lush green grass that invites all the wildlife to entertain you—your own natural sanctuary waiting to be explored. Nature surrounds you here, with frequent sightings of whistling wood ducks, sandhill cranes, deer, and more, creating a peaceful and vibrant wildlife backdrop. Tucked away in a quiet, desirable neighborhood, this property offers the rare combination of privacy, waterfront living, and convenience—just minutes from local restaurants, shopping, and everyday essentials. And best of all—NO HOA. Offered at $397,500, this is more than a home—it’s a lifestyle, a retreat, and an extraordinary opportunity to own a slice of Florida paradise. *Additional 8.2 acre island lot available at $97,000

561 Se 28th Street, Melrose

Listing courtesy of WATSON REALTY CORP. daveferro@watsonrealtycorp.com

$299,900
3 Beds 2 Baths TB8525712 MLS
Welcome home to this beautifully renovated 3-bedroom, 2-bath double-wide manufactured home situated on 1.01 private, wooded acres. Just minutes from Lake Santa Fe! Thoughtfully updated from top to bottom, this move-in-ready home offers the perfect blend of modern comfort, peaceful surroundings, and everyday functionality. Step inside to an open and spacious floor plan featuring a cozy fireplace in the living room, a beautifully updated kitchen with a center island ideal for cooking and entertaining, and a charming built-in hutch in the dining area. Large windows fill the home with natural light, creating a warm and inviting atmosphere throughout. Step outside to the expansive screened back porch, where you can relax with your morning coffee, entertain family and friends, or simply enjoy the beauty of nature from the comfort of your own backyard. One of the property’s biggest advantages is in a NO Flood Zone, giving you added freedom and potential savings on ownership costs, has a shed and generator. Located just minutes from the charming town of Melrose, you’ll enjoy a welcoming community known for its local art galleries, community events, scenic parks, and quaint restaurants with outdoor dining. Conveniently located near Keystone Heights and Gainesville, you’ll have easy access to shopping, dining, healthcare, and everyday conveniences while still enjoying the tranquility of country living. This beautiful gem will not last long, book your showing today!

145 Crystal Lake Drive, Melrose

Listing courtesy of RE/MAX MARKETING SPECIALISTS. 352-686-0540

$479,999
3 Beds 2 Baths GC541232 MLS
If you've been searching for a home where quality comes first, look no further. Built in 2021 with exceptional craftsmanship and attention to detail, this beautifully maintained 3-bedroom, 2-bath home sits on 2.35 peaceful acres with no HOA, offering the perfect balance of privacy, comfort, and modern convenience. From the moment you arrive, it's clear this home has been meticulously cared for. Inside, you'll find soaring ceilings, an open-concept layout, abundant natural light, and a thoughtfully designed split floor plan. The spacious kitchen flows seamlessly into the living and dining areas, creating an ideal space for everyday living and entertaining. Designed with long-term comfort in mind, the home is fully ADA accessible, featuring wide doorways, single-level living, and an accessible bathroom. One of the home's most practical features is the laundry room, conveniently accessible from both the primary suite and the main living area. Step onto the large screened porch and enjoy peaceful views of Big Lake Santa Fe, framed by magnificent live oak trees that create a tranquil setting where nature takes center stage. For those who love being on the water, the Lake Santa Fe Public Boat Ramp is just 2 miles away, making it easy to launch your boat, kayak, or paddleboard and enjoy all the lake has to offer. Beyond the home itself, the property offers exceptional versatility with an attached 2-car garage, a 2-car carport, and a separate 18' x 22' powered workshop/garage—perfect for projects, hobbies, additional vehicles, or lake toys. Built with durability and peace of mind in mind, this home also includes insulated garage walls, a whole-house generator connected to a buried 500-gallon propane tank, an active termite bond in place since construction, and countless thoughtful details that reflect the pride of ownership throughout. Whether you're enjoying coffee on the porch overlooking the lake, working on your next project in the workshop, or simply appreciating the quiet surroundings, this is the kind of home that's increasingly difficult to find—a home built with intention, maintained with care, and designed to be enjoyed for years to come. Quality never goes out of style. Come experience the difference for yourself.

7517 Ne 221st Street, Melrose

Listing courtesy of KELLER WILLIAMS GAINESVILLE REALTY PARTNERS. 352-240-0600

$200,000
3 Beds 2 Baths GC541389 MLS
Investor Opportunity on 3 Acres in Melrose! This 3-bedroom, 2-bathroom manufactured home offers incredible potential and is ready for your vision. Situated on 3 fully fenced acres of agricultural-zoned land, this property is perfect for those looking to create a private homestead, hobby farm, or investment property. Located in the desirable Ashley Lake Plantation community, you'll enjoy the peace and quiet of country living while remaining just minutes from everyday conveniences. Downtown Melrose, local restaurants, grocery stores, and shopping are just 5 minutes away. Bring your horses, goats, chickens, and other farm animals and take advantage of the freedom this property provides. With plenty of room to expand, garden, or simply enjoy the open space, this property offers endless possibilities for the right buyer. If you're looking for acreage, privacy, and a property with room to build equity, this Melrose gem is worth a look!

107 Green Oak Drive, Melrose

Listing courtesy of CB ISAAC REALTY. 352-475-2199

$369,900
2 Beds 2 Baths GC540380 MLS
SANTA FE CANAL WATERFRONT HOME Seems the Lake Region of North Central Florida is being discovered by so many now wanting out of the CITY TRAFFIC AND CHAOS and getting back to enjoying a rural lifestyle and lake living. Here in Historic Melrose Florida is this 2/2 all metal Morton Home located in a private community on a paved road. The home is uniquely designed with quality construction. The split floor plan allows private door access to either side, plus roadside. Just a few steps and you are at your screened-in dock with an open deck and sheltered boat lift. The property also includes a 20x20 2 car carport and a large 12x16 storage shed. The famous Santa Fe is a 6,000 acre fully recreational lake allowing you all types of activities: wake surfing, kayaking, tubing, fishing, jet skiing, swimming, sailing, and more. From your dock to the big lake, you're only minutes away. This location is also conveniently located for commuting to Gainesville, Palatka, Ocala, Starke, and Middleburg Florida - but the true highlight is being part of Historic Melrose. Yes, it’s only a one-light town, but it is alive with activity. Besides its natural beauty and friendly atmosphere this amazing little big town offers some fine restaurants, general shopping stores, fresh produce stands, doctors, a senior center, cultural activities, even at Mossman Hall there are art shows, dances, and various classes. Live music seems to be somewhere every week entertaining the folks in and around our amazing lake region. You're welcome to drive by this home anytime but be sure to visit the Historic District of Melrose - you'll notice the towns charm immediately and why many are wanting this special way of life out here in the Lake Region of North Central Florida. NOTE: This home may come completely furnished

529 Se 5th Avenue, Melrose

Listing courtesy of CENTURY 21 LAKESIDE REALTY. 352-475-1269

$899,000
3 Beds 3 Baths GC539093 MLS
Welcome to your Lake Retreat on Melrose Bay, Lake Santa Fe! Designed by renowned architect Ron Haase, this iconic, Old-Florida style home was designed as his family’s personal lake retreat. Filled with natural light, the open-concept great room, kitchen, and dining area create a warm, airy space ideal for both relaxed living and effortless entertaining. The kitchen features elegant stone countertops, brushed chrome appliances, and a cozy breakfast bar—perfect for greeting the sunrise through the easterly windows! Dine indoors or step onto the elevated deck and screened lanai to enjoy lake breezes and gorgeous sunsets! Thoughtfully designed to embrace Florida’s natural beauty, the home showcases wide overhangs, cedar trim, new wood flooring throughout, metal accent siding, cedar-lined closets, and Pella windows throughout—blending craftsmanship with timeless style. Nestled in the heart of historic Melrose, Melrose Bay is a peaceful no-wake zone with direct access to Lake Santa Fe. The Lake is celebrated for its pristine water quality, excellent fishing, kayaking, paddle boarding, and swimming! Enjoy the conveniences and activities of the eclectic Melrose community AND the serenity of this home and property. it is an easy walk, bike ride or golf cart trip from the property to Melrose for dining, art galleries, and supplies. Melrose is just 30 minutes from Gainesville, 20 minutes to Gainesville Regional Airport, and 90 minutes to Jacksonville. Experience the perfect harmony of architectural elegance, lakeside tranquility, and classic Florida charm in this one-of-a-kind waterfront home!

25608 Devonia Street, Melrose

Listing courtesy of REMAX SELECT PARTNERS. 850-525-7570

$385,000
3 Beds 2 Baths GC539187 MLS
Seller financing possible with acceptable terms & down payment!! Tucked away at the very end of Island Road, this charming rustic retreat offers a rare opportunity to enjoy true waterfront living on the Santa Fe Canal—just steps from where it opens into Lake Santa Fe. This 3-bedroom, 2-bath home blends cozy character with thoughtful updates, including a beautifully refreshed kitchen and bathrooms, along with a durable new metal roof for peace of mind. Inside, you’ll find warm, inviting spaces that make you feel right at home from the moment you walk in. Out back is where this property truly shines. A massive Florida room creates the ultimate entertaining space—complete with a built-in bar area and pool table—perfect for hosting friends, game nights, or simply relaxing after a day on the water. Even better, all furnishings can stay, making this a turnkey opportunity. Step outside and take in peaceful canal views from your backyard, with direct access to Lake Santa Fe just moments away. As the last home before the canal opens to the lake, you’ll enjoy a unique blend of privacy and prime positioning for boating, fishing, and waterfront living. Additional features include a large workshop with electric—ideal for hobbies, storage, or projects—and a newer dock ready for your boat and lake days. Whether you’re looking for a full-time residence, weekend getaway, or income-producing vacation rental, this one-of-a-kind property delivers the best of North Florida lake life.

6308 Island Road, Melrose

Listing courtesy of CB ISAAC REALTY. 352-475-2199

$285,000
3 Beds 2 Baths GC539149 MLS
Lake life starts here with deeded access to the highly sought-after Swan Lake, only a quick golf cart ride from your doorstep. This well-maintained 3-bedroom, 2-bathroom features a comfortable and inviting layout designed for everyday living. Situated on a desirable corner lot, outside you will enjoy a spacious yard, a storage shed for all of your lake gear, and a back patio to enjoy your morning coffee while listening to nature. Whether you're relaxing at home or hosting guests, this property provides the perfect balance of functionality and warmth. Spend your days enjoying boating, fishing, or soaking in peaceful lake views, all without the premium price of direct waterfront. Located in the heart of Melrose, you'll love the small-town feel while still having the luxury of both Comcast & Xfinity internet. If you've been searching for affordable lake-area living with access to one of the region's most desirable lakes--this is it!

102 Swans Nest Circle, Melrose

Listing courtesy of CB ISAAC REALTY. 352-475-2199

$995,000
4 Beds 5 Baths NS1087706 MLS
DIRECT LAKEFRONT- Lake Santa Fe, is rated one of the BEST natural spring fed lakes in Florida. Welcome Home to your dream family lake house! Nestled on a tranquil lot with panoramic water views, this stunning lakefront home is designed for both relaxation and entertaining. With its spacious living areas, it’s the perfect place to create unforgettable memories. The fully furnished main home features 3 generous bedrooms and 3.5 bathrooms, an open-concept kitchen and living room flowing onto a screened-in porch with stunning lake views. Upstairs you will find 2 large bedrooms, each with ensuite bathrooms along with a cozy second living area- ideal for guests. This property also features an oversized 3-car garage with ample storage for boats and lake gear. Above the garage you will find a fully finished 1-bedroom, 1-bathroom guest apartment with a full kitchen and living room- perfect for extended family, visitors, or Airbnb potential. This beautiful home sits on 0.69 areas, designed for outdoor enjoyment and easy lake access, less than a mile from the boat ramp with plenty of space to park a boat or RV. Enjoy your days on the lake or enjoying the two screened-in porches to soak in the lake breeze. This home isn’t just a property—it’s a lifestyle. Enjoy sun-soaked days by the water, evenings under the stars, and every special moment in between. Whether you're looking for a full-time residence or a weekend escape, this lakefront gem offers everything you need and more. This Amazing location is only 25 minutes to Gainesville, 5 minutes to downtown Melrose and 15 minutes to Keystone Heights. Big Lake Santa Fe is a 5800 acre, aquifer fed stable lake with amazing fishing, recreation and water sports. Come for the views and stay for the peace and relaxation in this turnkey lakefront home! While all information is believed to be accurate, measurements should be verified by potential buyers

2499 Se 30th Street, Melrose

Listing courtesy of MG REAL ESTATE GROUP. 386-314-9502

$450,900
3 Beds 2 Baths GC535624 MLS
Welcome to this touch of paradise hidden from the road. Approximately 600 ft from the road, this spacious 3 bedroom/ 2 bath brick home is situated on two parcels totaling 4.47 acres. Wood burning fireplace with built in benches on each side. Garage has been converted into a master bedroom with 2 built in closets, a bathroom, and a laundry room. Large kitchen with farmhouse sink, lots of counter space, soft close cabinets, and a pantry. All appliances stay. Lots of storage throughout the home. Built in Ikea shelves in family room. Enjoy your coffee while sitting out on the back deck overlooking the back yard. Chicken coop in backyard. Well bladder tank replaced within the last 10 yrs. Metal roof 1995 and HVAC installed 2002. Ceiling and interior walls recently painted. Shipping container used for storage. Green shed has electric. 300' frontage of Lake Serena. Two entrances on property. Country living at it's best! Additional Parcel ID: 10-09-23-0000-0282-0000/732 SR26 - 1.84 acres

730+732 State Road 26, Melrose

Listing courtesy of HELEN HERSEY REALTY. 352-473-8882

$1,795,000
5 Beds 6 Baths GC531395 MLS
Uniquely perched on a 15 ft bluff above Lake Santa Fe, this expansive custom lakefront estate offers a grand scale and timeless elegance, perfect for those seeking a luxurious retreat. The heart of the home is its open kitchen, designed for effortless entertaining, flowing seamlessly into a spacious living area with room for a grand piano and dining space, all framed by 2 story ceilings that amplify the sense of grandeur. Almost every room captures stunning lake views, immersing you in the serene beauty of the surroundings. A dramatic custom steel circular staircase with oak treads milled from the property is designed to preserve the breathtaking vistas and add an artistic touch. The primary suite, nestled on the third floor nearly 40 ft above the lake, is a true sanctuary of luxury and tranquility. It opens to a private porch where you can savor morning coffee or evening wine while gazing out over the shimmering lake—a perfect spot for quiet reflection. Adjacent to the suite, a cozy keeper room offers a private retreat for reading or relaxation, bathed in natural light and lake views. The primary bathroom elevates the experience with a spacious, curbless walk-in shower designed for seamless accessibility, a corner soaking tub ideal for unwinding after a day on the water, and a custom double vanity that adds a touch of elegance to your daily routine. For the young or young-at-heart, a secret children’s room offers a magical hideaway, accessible only through a wardrobe, evoking a sense of wonder. Inside, 4 children’s bunk beds create a cozy retreat for sleepovers or imaginative play, making this space a delightful surprise for families. This home is built for versatility and comfort, with porches on all four floors, each offering a unique perspective of the lake’s shimmering waters—perfect for morning coffees or evening gatherings. The elevator accesses all four floors including the full-size attic, featuring 8 ft ceilings, making the home fully accessible for all. The attic is plumbed for an additional bathroom and offers ample space to create more bedrooms, making it ideal for growing families or guests. The first floor is a self-sufficient 2-bedroom apartment, complete with its own kitchen and living areas, operating independently from the main house for ultimate flexibility. Step outside to the lakefront, where a gentle beach entry offers an easy walk-in swimming area, perfect for family fun or a refreshing dip. The ipe wood dock extends into the lake, featuring a boat lift for your watercraft and boasting over 10 ft of water depth at its end—ideal for boating enthusiasts. The sunsets here are magical, painting the sky in vibrant hues as you unwind. This home is truly unlike any other and must be seen in person to experience all it has to offer.

23014 Ne 69th Avenue, Melrose

Listing courtesy of SHEEPCO REAL ESTATE GROUP. 904-701-0860

The data relating to real estate for sale on this website comes in part from the Internet Data Exchange program of MLS Now and updated as of . Real estate listings held by brokerage firms other than Coldwell Banker Realty are marked with the Internet Data Exchange logo and detailed information about them includes the name of the listing broker(s).
IDX information is provided exclusively for consumers' personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing.
All information provided is deemed reliable but is not guaranteed and should be independently verified. © 2026 MLS Now. All Rights Reserved.