Melrose Real Estate

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Newest Listings in Melrose

$250,000

3 Beds ⋅ 3 Baths ⋅ A4712254 MLS

Short Sale. Opportunity knocks! This brick home needs complete rehab but has great bones and sits on over 6 private acres with a pond! Fenced in yard, huge workshop and pull through garage. The yard will need lots of work and clean up but is full of large mature oaks, citrus trees, and grape vines throughout the yard. 2 wells on the property. Newer solar panels. So much potential for the right buyer! Sold as-is.Our short sale is approved for $250k, however, the buyer will need to pay off ~39k in liens OUTSIDE of the purchase price, and pay off or assume the solar. The balance of the solar is 47k, but can be assumed at $256/month once the back due balance of ~$1500 is paid.

4505 Ne Cr 219a, Melrose

Listing courtesy of REID REAL ESTATE GROUP LLC. 860-416-1255

$55,000

GC544461 MLS

Waterfront lot for homes or modular homes only. Paved road frontage. The lot has not been cleared so the new owner can puck and choose the trees that will remain

101 Ashley Lake Drive, Melrose

Listing courtesy of CB ISAAC REALTY. 352-475-2199

$33,999

A4710571 MLS

Discover this 2-acre vacant parcel in the Keystone Heights area, offering a great opportunity to own land in a peaceful rural setting. The property features a combination of wooded areas and open space, with mature trees providing natural privacy and plenty of room to enjoy the outdoors. Located in a quiet area with no HOA, this lot is ideal for buyers seeking more space, fewer restrictions, and a break from busy city living. A well and septic system will be required. The location offers convenient access to Highway 100 and the amenities of Keystone Heights, including shopping, restaurants, parks, and nearby lakes. Orange Park, Palatka, and Gainesville are also within a reasonable drive, making this an appealing option for those who value privacy without being too far from everyday conveniences. Listing is for land only and comes As Is. Street addresses can be for listing purposes only and vacant land will receive a true street address once improved. I MAKE IT MY POLICY TO PUT ALL KNOWN INFORMATION ABOUT EACH LOT IN THE WRITE-UP DETAILS, SO IF YOU DON’T SEE THE ANSWER YOU’RE LOOKING FOR , PLEASE CONTACT THE COUNTY TO GATHER INFORMATION. PLEASE UNDERSTAND WHEN BUYING OR SELLING VACANT OR RAW LAND THIS IS USUALLY THE CASE. THE LISTING AGENT DOES NOT GUARANTEE THE ACCURACY OF THE INFORMATION IN THIS LISTING AND IS TO BE HELD HARMLESS OF ANY MISREPRESENTATION. BUYERS ARE ENCOURAGED TO DO THEIR OWN DUE DILIGENCE TO MAKE SURE THE LOT IS A GOOD FIT. SELLERS HAVE STATED THAT THEY WISH TO SELECT THE TITLE AGENCY FOR CLOSING. THEY ARE WILLING TO COVER THAT COST AT CLOSING. THANK YOU FOR LOOKING. THIS IS A FLAT FEE LIMITED-SERVICE LISTING.

8329 State Road 100, Melrose

Listing courtesy of NEW ALLIANCE GROUP REALTY. 941-650-7488

$479,000

3 Beds ⋅ 4 Baths ⋅ GC544180 MLS

Beautiful Seminole Ridge Home! This 3 bedroom 3.5 bath home has 3093 sq ft of living space and sits on 1.6 acres in a park like setting. The home was updated in 2024 with new roof, AC, and submersible well & tank. It has a spacious great room with vaulted ceilings and tubular skylights. The kitchen has granite countertops, a large pantry, stainless steel appliances, plenty of cabinetry, breakfast bar, and a breakfast nook for casual dining. The bedrooms have walk in closets and en suite bathrooms. The bedroom adjacent to the family room could be used as an in-law suite. The laundry room has a half bath and lots of storage. There’s an all purpose room off the kitchen with hot tub that leads to the screen porch and concrete patio. The home has a detached 2 carport and attached 1 car carport that connects to a workshop. The back yard has privacy fencing and a shed and the whole property is made up of three parcels, one in Bradford and two in Clay. Come and see this home will not last!

657 Se 2nd Avenue, Melrose

Listing courtesy of TREVOR WATERS REALTY INC. 352-473-7777

$263,500

3 Beds ⋅ 2 Baths ⋅ GC543849 MLS

***Seller is willing to contribute toward the buyer’s closing costs with an acceptable offer.*** Beautifully updated and move-in ready, this 3-bedroom, 2-bath home offers 1,829 square feet of living space in Melrose. The spacious family room features recessed lighting, large windows that bring in plenty of natural light, and plenty of room to relax, gather, or entertain. The open layout connects the family room to the dining area and updated kitchen, creating a bright and welcoming living space. The kitchen features white cabinetry, stainless steel appliances, plenty of counter space, and a large island with seating. LVP flooring runs throughout the main living areas, while both bathrooms have been beautifully updated with modern finishes and tile work. An indoor laundry room adds everyday convenience. Outside, you'll find a spacious backyard with mature trees and plenty of room to enjoy the outdoors. The home also features a 2023 roof. Conveniently located just minutes from the upcoming Aldi in Melrose, Winn-Dixie, Keystone Beach and Park, local restaurants, and everyday services, with easy access to both Keystone Heights and Gainesville. Enjoy a quieter setting while still keeping the places you need close by.

6898 Cr 214, Melrose

Listing courtesy of KELLER WILLIAMS GAINESVILLE REALTY PARTNERS. 352-240-0600

$599,999

3 Beds ⋅ 2 Baths ⋅ GC543864 MLS

WATERFRONT LIVING ON THE CANAL TO LAKE SANTA FE! This spacious 3-bedroom, 2-bath waterfront home offers 2,301 square feet of heated and cooled living space with an ideal blend of comfort, functionality, and outdoor living. The interior features a welcoming living room, dedicated office area, dining space, and a well-appointed kitchen with prep island—perfect for everyday living and entertaining. The oversized primary bedroom is truly impressive, measuring approximately 31 feet in length and offering plenty of room to relax and unwind. Step outside to the lanai and take in peaceful waterfront views overlooking the boat house and boat lift. The outdoor living area is designed for enjoying the Florida lifestyle, featuring an inviting in-ground pool and hot tub. With canal access to Lake Santa Fe, this property offers an exceptional opportunity for boating, recreation, and waterfront enjoyment right at home. A unique combination of spacious indoor living, private outdoor amenities, and direct water access makes this Lake Santa Fe-area home a must-see.

241 Se 5th Avenue, Melrose

Listing courtesy of CB ISAAC REALTY. 352-475-2199

$65,000

GC543660 MLS

Discover the perfect place to build your dream home in beautiful Melrose, Florida! This stunning 1-acre vacant lot in the charming Seminole Ridge subdivision offers the space, tranquility, and natural beauty you've been looking for. With paved road access from SE 3rd Ave and SE 4th Ave, this property provides convenient access while maintaining the peaceful atmosphere of a quiet, welcoming community. One of the standout features is access to Lake Santa Fe through a private boat ramp, offering opportunities to enjoy boating, fishing, and the laid-back lake lifestyle that makes this area so special. Whether you're dreaming of a peaceful retreat or a place to build your forever home, this beautiful lot is ready for your vision. Located in the quiet, charm-filled town of Melrose, you'll enjoy the best of small-town living surrounded by Florida's natural beauty. Bring your plans and start building the home you've always imagined!

Se 4th Ave, Melrose

Listing courtesy of MOMENTUM REALTY - GAINESVILLE. 904-903-1558

$259,900

3 Beds ⋅ 2 Baths ⋅ GC543401 MLS

If being near Lake Santa Fe and lower property taxes sounds like what you're looking for, this home is for you. With only being five minutes from the lake, it makes backing down the boat, riding your jet ski, and fishing easy to do. On 1.85 acres, you'll immediately feel at ease as soon as you enter the property. This beautiful and unique concrete block home is elevated off the ground with no worries of flooding and invites you in with its natural light and warm, welcoming atmosphere. With an open layout, this home is perfect for entertaining, and areas to work from home or have a playroom area. You'll find 3 cozy bedrooms and 2 charming bathrooms here. Beyond the kitchen is a Florida Room with beautiful nature views where doing laundry will feel more enjoyable and less like a chore. Right outside the fully-fenced front and backyard, sits raised garden beds waiting for your plants and green thumb. There is a large garage perfect for storing your tools, using it as a workshop, housing your outdoor toys, or the perfect opportunity if you have a business - with its own separate electric meter! Around the back of the home you can access the basement where your water heater, plumbing and water softener system are all situated for easy access. Beautiful fruit trees (loquat, kumquat and orange) stand throughout the property. Bonus is an RV hookup nestled in the rear of the property. This home is situated in Melrose (Putnam County) conveniently located 20-30 minutes to Gainesville, providing a much smoother commute compared to other surrounding cities. Located throughout the charming town are local-loved restaurants such as Fryers, Gator Bait, and Blue Water Bay and beautiful parks such as Jill McGuire Santa Fe Lake Park, Melrose Bay Park, and Melrose Heritage Park. You can have it all here with an idyllic retreat at home, lake living, small-town charm and nearly everything just around the corner! 5 year old Roof, HVAC, and Water Heater. New Roof on Garage/Workshop. 100% Financing Available!

752 N State Road 21, Melrose

Listing courtesy of WATSON REALTY CORP- TIOGA. 352-274-2600

$219,990

3 Beds ⋅ 2 Baths ⋅ GC543118 MLS

GREAT LOCATION JUST STEPS TO SANTE FE LAKE. CAN BE A GOOD "GET AWAY ESCAPE HOME" FOR ANYONE. NOT A LARGE PLACE BUT HAS A PLEASANT COUNTRY CHARM. 3RD BEDROOM HAS A BUILT IN MURPHY BED. VERY POPULAR AREA WITH THE SNOW BIRDS. PROBABLY A GREAT SHORT TERM RENTAL OPPORTUNITY FOR EXTRA INCOME. JUST MINUTES TO MELROSE TO THE EAST AND GAINESVILLE TO THE WEST. SEVERAL EXTRA STORAGE BUILDINGS STAY. GREAT PLACE FOR PEACE AND QUIET.

7217 Ne 221st Street, Melrose

Listing courtesy of REMAX SELECT PARTNERS. 850-525-7570

$1,190,000

6 Beds ⋅ 6 Baths ⋅ GC543412 MLS

Welcome to an extraordinary lakefront retreat where space, character, and spectacular water views come together on beautiful Lake Rosa in Melrose, Florida. This one-of-a-kind property offers not just one exceptional home, but two residences, creating an incredible opportunity for a large family, multigenerational living, guests, or those looking for a private lakefront getaway with additional space on an expansive 9.2 acres. The magnificent main residence offers an impressive 5,187 square feet of heated and cooled living space, featuring 4 bedrooms and 4 1/2 bathrooms. From the moment you drive onto the property, you will feel you have entered a park with the beautifully manicured grounds, which include 1000 planted, mature camellias. Once inside the main house you will take in vaulted ceilings and the expansive and breathtaking lake views that set the tone for relaxed lakefront living. You'll find wonderful spaces designed for both entertaining and everyday enjoyment, including two loft areas, a cozy fireplace, wet bar, and a wine cellar—perfect for evenings spent with friends and family after a day on the lake. The generous living spaces provide plenty of room to spread out while still maintaining the warm, inviting feel you'd expect from a true lake home. The outside decks from this home give over 3000 sq ft of additional space to enjoy the outdoors from many rooms and levels of the home. And then there's the second residence, offering an additional 2,496 square feet of heated and cooled living space, with 2 bedrooms and 1 bathroom. Complete with its own deck overlooking the lake, this separate home is ideal for guests, extended family, a caretaker, or anyone who wants their own private space while still being just steps from all the lakefront fun. With a combined 7,683 square feet of heated and cooled living space and 6 total bedrooms, this is far more than a home—it's a lakefront lifestyle and an opportunity that's hard to duplicate. Imagine morning coffee with the lake as your backdrop, afternoons enjoying the water from your private dock and evenings gathered around the fireplace or relaxing on the deck as the day winds down. Whether you're looking for a spectacular full-time residence, a weekend escape, or a property designed for entertaining generations of family and friends, this one delivers the space, setting, and character to make lake memories for years to come. Come experience the magic of Lake Rosa for yourself—this is lake living with room for everyone!

202 Mason Road, Melrose

Listing courtesy of REMAX SELECT PARTNERS. 850-525-7570

$398,000

2 Beds ⋅ 2 Baths ⋅ GC543379 MLS

Nestled on Island Road in Melrose, escape to your private waterfront oasis on the desirable Santa Fe Canal, with direct access to the expansive 6,000-acre Santa Fe Lake. This beautifully updated 2-bedroom, 2-bath home blends indoor comfort with outdoor Florida living-all just minutes from a public boat ramp and picnic area. Detached 2-car garage for storage, projects, or extra parking. Sprinkler system keeps the landscape lush with minimal effort. Canal-side deck ideal for cookouts, fishing, or relaxing by the water. Recent major updates: HVAC (2023), water heater (2024) plus many more recent improvements throughout. Vaulted ceiling with a stone-accent gas fireplace creates a warm, open great room. Split bedroom floor plan for privacy and flexibility. Enclose sunroom-perfect for morning coffee or enjoying outdoors from inside.

5930 Island Road, Melrose

Listing courtesy of HELEN HERSEY REALTY. 352-473-8882

$389,700

3 Beds ⋅ 2 Baths ⋅ GC543255 MLS

BEAUTIFUL NEW CONSTRUCTION IN DESIRABLE MELROSE! Welcome home to this beautifully crafted new construction by D.R. Baker Construction, offering quality, comfort, and thoughtful design on a spacious half-acre lot in desirable Melrose, Bradford County. Just one block from Lake Santa Fe, this 3-bedroom, 2-full-bath home offers an inviting blend of modern style and relaxed Florida living. Step inside to a bright and welcoming open-concept floor plan featuring over 1,551 square feet of living space, high ceilings, and abundant natural light. The spacious kitchen is designed for both everyday living and entertaining, with an open layout and center island that creates the perfect gathering spot for family and guests. The desirable split-bedroom floor plan provides privacy for the spacious primary suite, which features elegant tray ceilings, a generous walk-in closet, and a light and bright primary bathroom. An oversized inside utility room provides excellent storage and workspace, adding everyday convenience to this thoughtfully designed home. Step outside and enjoy your morning coffee or unwind at the end of the day from either the front or back covered porch. The beautiful half-acre lot provides room to enjoy the peaceful surroundings and embrace the laid-back lifestyle that makes Melrose so special. Located in Melrose, Bradford County, with an easy commute to Gainesville, Orange Park, and Palatka, this home offers a wonderful opportunity to enjoy new construction, a beautiful setting, and convenient access to surrounding communities. Come see the quality and beauty of a D.R. Baker Construction home for yourself!

377 Se 4th Avenue, Melrose

Listing courtesy of WATSON REALTY CORP. daveferro@watsonrealtycorp.com

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The data relating to real estate for sale on this web site comes in part from the Broker Reciprocity™ program of the Multiple Listing Service of Greater Cincinnati. Real estate listings held by brokerage firms other than our company are marked with the Broker Reciprocity™ logo (the small house as shown to the left) and detailed information about them includes the name of the listing brokers. This data is up-to-date as of . Copyright 2026, MLS of Greater Cincinnati, Inc. All rights reserved. Information deemed reliable but not guaranteed.

The data relating to real estate for sale on this website comes in part from the Broker Reciprocity program of the Dayton Area Board of Realtors® MLS IDX Database. Real estate listings from the Dayton Area Board of Realtors® MLS IDX Database held by brokerage firms other than eXp Realty are marked with the IDX logo and are provided by the Dayton Area Board of Realtors® MLS IDX Database. Information is provided for consumers' personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in. Copyright© 2026 Dayton Area Board of Realtors®

Melrose Real Estate

Newest Listings in Melrose

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